Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.57 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | CTRL | P40313 | 1/20 | 0.43 |
| ▸ | CTRB2 | Q6GPI1 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29905548 | 0.93 | F2 (0.62) | F2KLKB1 | |
| SCHEMBL20473837 | 0.88 | F2 (0.64) | F2KLKB1 | |
| SCHEMBL29905488 | 0.87 | F2 (0.55) | F2KLKB1PLGF11KLK1 | |
| SCHEMBL18039789 | 0.85 | F2 (0.51) | F2KLKB1PLGF11KLK1 | |
| SCHEMBL18039777 | 0.85 | F2 (0.50) | F2KLKB1 | |
| SCHEMBL29905427 | 0.85 | F2 (0.64) | F2KLKB1 | |
| SCHEMBL29905184 | 0.84 | F2 (0.69) | F2KLKB1PLGF11KLK1 | |
| SCHEMBL18039994 | 0.83 | F2 (0.53) | F2KLKB1 | |
| SCHEMBL20473867 | 0.83 | F2 (0.50) | F2KLKB1PLGF11KLK1 | |
| SCHEMBL18039826 | 0.83 | F2 (0.50) | F2KLKB1PLGF11KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3261639-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON INT CORPORATION (US) | 2022-08-24 | — | — | EP | claimed |
| EP-3261639-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON INT CORPORATION (US) | 2022-08-24 | — | — | EP | disclosed |