SCHEMBL29905616

SCHEMBL29905616

CC1(C)C2[C@@H](CO)N(Cc3ccccc3)CC21F

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.45
SIGMAR1 Q99720 6/20 0.38
MAPT P10636 1/20 0.38
MEN1 O00255 1/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.38
GAA P10253 2/20 0.37
GRM6 O15303 1/20 0.36
TMEM97 Q5BJF2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31336622 0.74 GBA1 (0.44) GBA1SIGMAR1MAPTGRM6
SCHEMBL23556332 0.70 GBA1 (0.68) GBA1SIGMAR1GAA
SCHEMBL23556330 0.70 GBA1 (0.68) GBA1SIGMAR1GAA
SCHEMBL24337537 0.70 GBA1 (0.68) GBA1SIGMAR1GAA
SCHEMBL25484822 0.70 GBA1 (0.68) GBA1SIGMAR1GAA
SCHEMBL12604944 0.69 GBA1 (0.47) GBA1SIGMAR1MAPTGAA
SCHEMBL16316517 0.69 GBA1 (0.47) GBA1SIGMAR1MAPTGAA
SCHEMBL14450892 0.69 GBA1 (0.47) GBA1SIGMAR1MAPTGAA
SCHEMBL26186815 0.68 MAPT (0.59) GBA1SIGMAR1MAPTGAA
SCHEMBL26187013 0.68 MAPT (0.59) GBA1SIGMAR1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115043900-B Peptoid compound and application thereof in preparation of 2019-nCoV main protease inhibitor 深圳博瑞医药科技有限公司 2025-02-18 CN disclosed
CN-115043900-A Peptide-like compound and application thereof in preparation of 2019-nCoV main protease inhibitor 深圳博瑞医药科技有限公司 2022-09-13 CN disclosed