⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9133756 | 0.83 | CYP19A1 (0.42) | — | |
| SCHEMBL28023189 | 0.81 | CYP19A1 (0.45) | — | |
| SCHEMBL86131 | 0.81 | — | — | |
| SCHEMBL459642 | 0.81 | CYP19A1 (0.48) | — | |
| Bromide SCHEMBL10990647 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL4251018 | 0.79 | — | — | |
| Fluoride SCHEMBL28816395 | 0.79 | — | — | |
| SCHEMBL17902707 | 0.77 | — | — | |
| SCHEMBL6271157 | 0.77 | — | — | |
| SCHEMBL76770 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114599651-A | Indazoles as inhibitors of hematopoietic progenitor kinase 1(HPK1) and methods of use thereof | 第一生物治疗股份有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-108174603-B | 1-heteroaryl-indoline-4-carboxamides as GPR52 modulators | 阿芮纳制药有限公司 | 2021-07-02 | — | — | CN | claimed |
| CN-114642735-A | Methods, compositions and systems for delivering therapeutic and diagnostic agents into cells | 菲泽尔克斯公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-114599653-A | Indazoles as inhibitors of hematopoietic progenitor kinase 1(HPK1) and methods of use thereof | 第一生物治疗股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114599651-A | Indazoles as inhibitors of hematopoietic progenitor kinase 1(HPK1) and methods of use thereof | 第一生物治疗股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-107530436-B | Methods, compositions and systems for delivering therapeutic and diagnostic agents into cells | 菲泽尔克斯公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-108174603-B | 1-heteroaryl-indoline-4-carboxamides as GPR52 modulators | 阿芮纳制药有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-108410134-A | A kind of fibrous composite composition epoxy resin and its application | 苏州银禧新能源复合材料有限公司 | 2018-08-17 | — | — | CN | disclosed |
| CN-104936962-B | Therapeutically active oxazoline derivatives | UCB生物制药私人有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-103396551-B | A kind of imidazolyl modified silicon oil and preparation and application thereof | SHENZHEN TAIKANG NEW MATERIAL TECHNOLOGY Co.,Ltd. (CN) | 2015-09-30 | — | — | CN | disclosed |
| CN-104936962-A | Therapeutically active oxazoline derivatives | UCB PHARMA SA | 2015-09-23 | — | — | CN | disclosed |
| EP-1370531-A1 | PHENYLALANINE ENAMIDE DERIVATIVES POSSESSING A CYCLOBUTENE GROUP, FOR USE AS INTEGRIN INHIBITORS | Celltech R & D Limited (GB) | 2003-12-17 | — | — | EP | disclosed |
| US-20020169336-A1 | Phenylalanine enamide derivatives | UCB PHARMA S.A. (BE) | 2002-11-14 | — | — | US | disclosed |
| WO-2002068393-A1 | PHENYLALANINE ENAMIDE DERIVATIVES POSSESSING A CYCLOBUTENE GROUP, FOR USE AS INTEGRIN INHIBITORS | CELLTECH R & D LIMITED (GB) | 2002-09-06 | — | — | WO | disclosed |
| US-6166036-A | Lp(a)-lowering agent and apolipoprotein (a) formation suppressing agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-1000620-A1 | Lp(a)-LOWERING AGENTS AND APOPROTEIN (a) PRODUCTION INHIBTORS | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5439927-A | For potassium channel opening, hypotensive agents, broncho- or vasodilators, gastrointestinal disorders | MITSUBISHI KASEI CORPORATION (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5332833-A | Potassium channel modulator, hypotensive, hypersensitive colon syndrome, asthma, enteritis | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5145865-A | Fatty acid, cholesterol synthesis inhibitors; enzyme inhibitors; antilipemic agents | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0393607-A2 | Phenylcarboxylic acid derivatives having a hetero ring | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |