Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 13/20 | 0.78 |
| ▸ | F2 | P00734 | 10/20 | 0.77 |
| ▸ | KLK1 | P06870 | 3/20 | 0.68 |
| ▸ | PLG | P00747 | 1/20 | 0.68 |
| ▸ | F11 | P03951 | 1/20 | 0.68 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.68 |
| ▸ | CTRL | P40313 | 1/20 | 0.68 |
| ▸ | CTRB2 | Q6GPI1 | 1/20 | 0.68 |
| ▸ | CTRC | Q99895 | 1/20 | 0.68 |
| ▸ | F10 | P00742 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18039815 | 1.00 | KLKB1 (0.78) | KLKB1F2KLK1PLGF11 | |
| SCHEMBL20506150 | 0.88 | KLKB1 (1.00) | KLKB1F2KLK1PLGF11 | |
| SCHEMBL20506397 | 0.87 | F2 (1.00) | KLKB1F2KLK1PLGF11 | |
| SCHEMBL29905897 | 0.87 | F2 (1.00) | KLKB1F2KLK1PLGF11 | |
| SCHEMBL18040048 | 0.85 | KLKB1 (0.73) | KLKB1F2KLK1PLGF11 | |
| SCHEMBL29905946 | 0.85 | F2 (0.77) | KLKB1F2KLK1PLGF11 | |
| SCHEMBL29905438 | 0.85 | F2 (0.81) | KLKB1F2KLK1PLGF11 | |
| Hydrochloric Acid SCHEMBL29905263 | 0.84 | F2 (0.76) | KLKB1F2KLK1PLGF11 | |
| Hydrochloric Acid SCHEMBL18039935 | 0.84 | F2 (0.76) | KLKB1F2KLK1PLGF11 | |
| SCHEMBL20506097 | 0.84 | KLKB1 (0.95) | KLKB1F2KLK1PLGF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3261639-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON INT CORPORATION (US) | 2022-08-24 | — | — | EP | disclosed |