Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 9/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL23830267 | 1.00 | BTK (0.56) | BTKKLKB1HSD17B10EGLN1 | |
| SCHEMBL18816755 | 0.95 | BTK (0.60) | BTKKLKB1HSD17B10EGLN1 | |
| SCHEMBL23769517 | 0.95 | BTK (0.60) | BTKKLKB1HSD17B10EGLN1 | |
| SCHEMBL20549625 | 0.94 | BTK (0.59) | BTKKLKB1HSD17B10EGLN1 | |
| SCHEMBL23774014 | 0.86 | BTK (0.59) | BTKKLKB1HSD17B10 | |
| SCHEMBL23830268 | 0.86 | BTK (0.54) | BTKKLKB1 | |
| Trifluoroacetic Acid SCHEMBL31075300 | 0.85 | HSD17B10 (0.43) | BTKKLKB1HSD17B10EGLN1 | |
| Trifluoroacetic Acid SCHEMBL29906618 | 0.84 | BTK (0.49) | BTKKLKB1HSD17B10EGLN1 | |
| Trifluoroacetic Acid SCHEMBL23830173 | 0.84 | BTK (0.49) | BTKKLKB1HSD17B10EGLN1 | |
| SCHEMBL18795023 | 0.83 | BTK (0.59) | BTKKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120287-B | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-116120287-A | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-115052873-A | Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors | 勃林格殷格翰国际有限公司 | 2022-09-13 | — | — | CN | disclosed |