Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21713003 | 1.00 | KLKB1 (0.60) | KLKB1 | |
| SCHEMBL30140695 | 0.96 | KLKB1 (0.56) | KLKB1 | |
| SCHEMBL23469682 | 0.93 | KLKB1 (0.60) | KLKB1 | |
| SCHEMBL23769626 | 0.87 | KLKB1 (0.48) | KLKB1 | |
| SCHEMBL23769195 | 0.87 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL23769637 | 0.87 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL23769198 | 0.87 | KLKB1 (0.49) | KLKB1 | |
| SCHEMBL24105354 | 0.86 | KLKB1 (0.51) | KLKB1 | |
| SCHEMBL23769171 | 0.86 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL23769681 | 0.85 | KLKB1 (0.46) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120287-B | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-113039181-B | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-116120287-A | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-110546146-B | Heteroaryl carboxamide derivatives as plasma kallikrein inhibitors | 勃林格殷格翰国际有限公司 | 2023-02-21 | — | — | CN | disclosed |
| CN-115052873-A | Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors | 勃林格殷格翰国际有限公司 | 2022-09-13 | — | — | CN | disclosed |