Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 6/20 | 0.50 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | AXL | P30530 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23210998 | 1.00 | FGFR3 (0.50) | FGFR3MAP4K1FGFR1ACVR1FGFR2 | |
| SCHEMBL23210878 | 0.90 | FGFR3 (0.41) | FGFR3MAP4K1FGFR1ACVR1FGFR2 | |
| SCHEMBL29906931 | 0.90 | FGFR3 (0.41) | FGFR3MAP4K1FGFR1ACVR1FGFR2 | |
| SCHEMBL29906830 | 0.90 | TTK (0.45) | FGFR3MAP4K1FGFR1ACVR1FGFR2 | |
| SCHEMBL23210780 | 0.90 | TTK (0.45) | FGFR3MAP4K1FGFR1ACVR1FGFR2 | |
| SCHEMBL23210641 | 0.89 | MAP4K1 (0.44) | FGFR3MAP4K1FGFR1ACVR1FGFR2 | |
| SCHEMBL29906832 | 0.89 | MAP4K1 (0.44) | FGFR3MAP4K1FGFR1ACVR1FGFR2 | |
| SCHEMBL30308775 | 0.89 | FGFR3 (0.40) | FGFR3MAP4K1FGFR1ACVR1FGFR2 | |
| SCHEMBL23210942 | 0.88 | FGFR3 (0.41) | FGFR3MAP4K1FGFR1ACVR1FGFR2 | |
| SCHEMBL29906834 | 0.88 | FGFR3 (0.41) | FGFR3MAP4K1FGFR1ACVR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115835908-A | Bicyclic heterocycles as FGFR inhibitors | 因赛特公司 | 2023-03-21 | — | — | CN | claimed |
| EP-4045151-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-08-24 | — | — | EP | claimed |
| CN-115835908-A | Bicyclic heterocycles as FGFR inhibitors | 因赛特公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-4045151-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-08-24 | — | — | EP | disclosed |