Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 19/20 | 0.53 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29907155 | 1.00 | PARP1 (0.53) | PARP1PARP2 | |
| SCHEMBL30493567 | 0.89 | PARP1 (0.54) | PARP1PARP2 | |
| SCHEMBL25193100 | 0.89 | PARP1 (0.54) | PARP1PARP2 | |
| SCHEMBL29907151 | 0.87 | PARP1 (0.53) | PARP1 | |
| SCHEMBL25093040 | 0.84 | PARP1 (0.54) | PARP1 | |
| SCHEMBL24649793 | 0.84 | PARP1 (0.54) | PARP1 | |
| SCHEMBL26451092 | 0.84 | PARP1 (0.57) | PARP1PARP2 | |
| SCHEMBL25791405 | 0.81 | PARP1 (0.54) | PARP1PARP2 | |
| SCHEMBL25605323 | 0.80 | PARP1 (0.67) | PARP1PARP2 | |
| SCHEMBL24649820 | 0.79 | PARP1 (0.47) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022222965-A1 | PYRIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-10-27 | — | — | WO | disclosed |