Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 8/20 | 0.37 |
| ▸ | RET | P07949 | 8/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23210866 | 1.00 | BUB1 (0.37) | BUB1RETCACNA1HGRIN1GRIN2B | |
| SCHEMBL23211102 | 0.89 | BUB1 (0.35) | BUB1RETCACNA1HGRIN2B | |
| SCHEMBL29008859 | 0.89 | BUB1 (0.37) | BUB1RETCACNA1HGRIN1GRIN2B | |
| SCHEMBL29907154 | 0.89 | RET (0.36) | BUB1RETCACNA1H | |
| SCHEMBL23210675 | 0.89 | RET (0.36) | BUB1RETCACNA1H | |
| SCHEMBL23211100 | 0.88 | RET (0.35) | BUB1RETCACNA1HGRIN1GRIN2B | |
| SCHEMBL29907070 | 0.85 | BUB1 (0.42) | BUB1GRIN1GRIN2B | |
| SCHEMBL23210943 | 0.85 | BUB1 (0.42) | BUB1GRIN1GRIN2B | |
| SCHEMBL23263997 | 0.85 | AAK1 (0.37) | BUB1RETCACNA1HGRIN1GRIN2B | |
| SCHEMBL29907095 | 0.85 | AAK1 (0.37) | BUB1RETCACNA1HGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115835908-A | Bicyclic heterocycles as FGFR inhibitors | 因赛特公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-4045151-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-08-24 | — | — | EP | disclosed |