Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 6/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23210993 | 1.00 | BUB1 (0.34) | BUB1MC4RUCHL1HCRTR1HCRTR2 | |
| SCHEMBL23210980 | 0.83 | S1PR1 (0.32) | — | |
| SCHEMBL23211130 | 0.82 | NPC1 (0.34) | KDM4EMAPT | |
| SCHEMBL23210934 | 0.81 | RET (0.35) | BUB1CD274 | |
| SCHEMBL29907063 | 0.81 | RET (0.35) | BUB1CD274 | |
| SCHEMBL29907043 | 0.81 | BUB1 (0.36) | BUB1HCRTR1HCRTR2CNR1CNR2 | |
| SCHEMBL23210936 | 0.81 | BUB1 (0.36) | BUB1HCRTR1HCRTR2CNR1CNR2 | |
| SCHEMBL29907074 | 0.80 | RET (0.33) | BUB1CD274 | |
| SCHEMBL23211003 | 0.80 | RET (0.33) | BUB1CD274 | |
| SCHEMBL23211137 | 0.79 | RET (0.35) | UCHL1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045151-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-08-24 | — | — | EP | disclosed |