Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23210995 | 1.00 | BUB1 (0.39) | BUB1KDM4EALDH1A1POLBGAA | |
| SCHEMBL23210986 | 0.90 | BUB1 (0.39) | BUB1KDM4EALDH1A1KMT2APIK3CD | |
| SCHEMBL29907069 | 0.90 | BUB1 (0.39) | BUB1KDM4EALDH1A1KMT2APIK3CD | |
| SCHEMBL23211078 | 0.85 | BUB1 (0.35) | BUB1KDM4EALDH1A1KMT2APIK3CD | |
| SCHEMBL29907060 | 0.84 | PIK3CD (0.36) | BUB1KDM4EALDH1A1HTTKMT2A | |
| SCHEMBL23211015 | 0.84 | PIK3CD (0.36) | BUB1KDM4EALDH1A1HTTKMT2A | |
| SCHEMBL29907043 | 0.83 | BUB1 (0.36) | BUB1GAAHTTKMT2ANPSR1 | |
| SCHEMBL23210936 | 0.83 | BUB1 (0.36) | BUB1GAAHTTKMT2ANPSR1 | |
| SCHEMBL23210943 | 0.76 | BUB1 (0.42) | BUB1KDM4EALDH1A1POLBGAA | |
| SCHEMBL29907070 | 0.76 | BUB1 (0.42) | BUB1KDM4EALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115835908-A | Bicyclic heterocycles as FGFR inhibitors | 因赛特公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-4045151-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2022-08-24 | — | — | EP | disclosed |