Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27147442 | 1.00 | KRAS (0.55) | KRAS | |
| SCHEMBL30725810 | 0.92 | KRAS (0.60) | KRAS | |
| SCHEMBL29907500 | 0.90 | KRAS (0.52) | KRAS | |
| SCHEMBL29907611 | 0.90 | KRAS (0.43) | KRAS | |
| SCHEMBL27148647 | 0.90 | KRAS (0.59) | KRAS | |
| SCHEMBL27151967 | 0.88 | KRAS (0.53) | KRAS | |
| SCHEMBL27218584 | 0.87 | KRAS (0.51) | KRAS | |
| SCHEMBL23300947 | 0.87 | KRAS (0.58) | KRAS | |
| SCHEMBL30996229 | 0.87 | KRAS (0.58) | KRAS | |
| SCHEMBL31129087 | 0.87 | KRAS (0.58) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4053118-A1 | SUBSTITUTED HETEROCYCLIC FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2022-09-07 | — | — | EP | disclosed |