SCHEMBL29907490

SCHEMBL29907490

CC(C)(O)c1ccc(NC(=O)c2cc(C(C)(C)O)nn(-c3ccccc3OCC(F)(F)F)c2=O)cc1

nearest known ligand 0.75

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
UGCG Q16739 8/20 0.75
MAPT P10636 3/20 0.44
THRB P10828 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TP53 P04637 2/20 0.40
P2RY1 P47900 1/20 0.40
CRACR2A Q9BSW2 2/20 0.39
RXFP1 Q9HBX9 1/20 0.39
SCN9A Q15858 2/20 0.39
NR3C1 P04150 1/20 0.38
S1PR1 P21453 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29907436 0.92 UGCG (0.64) UGCGMAPTTHRBSMN1; SMN2TP53
SCHEMBL29907410 0.91 UGCG (0.75) UGCGMAPTTHRBSMN1; SMN2P2RY1
SCHEMBL29907628 0.90 UGCG (0.61) UGCGMAPTTHRBSMN1; SMN2TP53
SCHEMBL29907503 0.89 UGCG (0.60) UGCGMAPTTHRBSMN1; SMN2TP53
SCHEMBL29907426 0.86 UGCG (1.00) UGCGMAPTSCN9A
SCHEMBL29907407 0.84 UGCG (0.61) UGCGMAPTTHRBSMN1; SMN2P2RY1
SCHEMBL29907428 0.80 UGCG (0.60) UGCGP2RY1SCN9A
SCHEMBL29907592 0.80 UGCG (1.00) UGCGMAPTSMN1; SMN2RXFP1S1PR1
SCHEMBL29601829 0.80 UGCG (0.59) UGCGP2RY1
SCHEMBL29907497 0.79 UGCG (0.81) UGCGSCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220289679-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220289679-A1 HETEROCYCLIC COMPOUND GBA1, GBA2, GALC UGCG 10/4885MAPT 772/4885THRB 4857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.