SCHEMBL29907665

SCHEMBL29907665

Cc1cc(C(=O)Nc2ccc(C(C)(C)O)nc2)c(=O)n(-c2ccccc2OCC(F)F)n1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
UGCG Q16739 5/20 0.47
PTGES O14684 1/20 0.40
TSHR P16473 1/20 0.40
MET P08581 2/20 0.38
AXL P30530 2/20 0.38
TYRO3 Q06418 2/20 0.38
MERTK Q12866 2/20 0.38
CRACR2A Q9BSW2 1/20 0.37
HCRTR2 O43614 5/20 0.37
HCRTR1 O43613 4/20 0.37
TGFBR1 P36897 1/20 0.37
RXFP1 Q9HBX9 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
P2RY1 P47900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29907624 0.93 UGCG (0.44) UGCGPTGESTSHRMETAXL
SCHEMBL29601829 0.90 UGCG (0.59) UGCGTSHRMETAXLTYRO3
SCHEMBL29907407 0.89 UGCG (0.61) UGCGMETAXLTYRO3MERTK
SCHEMBL29907456 0.86 UGCG (0.64) UGCGPTGESMETAXLTYRO3
SCHEMBL29907424 0.86 UGCG (0.51) UGCGTSHRMETAXLTYRO3
SCHEMBL29907458 0.84 UGCG (0.47) UGCGPTGESMETAXLTYRO3
SCHEMBL29602191 0.84 UGCG (0.46) UGCGTSHRMETAXLTYRO3
SCHEMBL29907563 0.84 TSHR (0.45) UGCGTSHRMETAXLTYRO3
SCHEMBL29907661 0.83 UGCG (0.47) UGCGPTGESMETAXLTYRO3
SCHEMBL29601644 0.82 KMT2A (0.49) UGCGRXFP1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220289679-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220289679-A1 HETEROCYCLIC COMPOUND GBA1, GBA2, GALC UGCG 10/4885PTGES 3127/4885TSHR 3896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.