Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.66 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21730362 | 1.00 | ADORA2A (0.68) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29987757 | 0.90 | ADORA2A (0.56) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21722597 | 0.88 | ADORA2A (0.67) | ADORA2AADORA1ADORA2B | |
| SCHEMBL17768693 | 0.88 | ADORA2A (0.70) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22552001 | 0.83 | ADORA2A (0.75) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22552033 | 0.83 | ADORA2A (0.72) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22242450 | 0.81 | ADORA2A (0.69) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21722319 | 0.81 | ADORA2A (0.71) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22552084 | 0.81 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL30175468 | 0.81 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-10-14 | — | — | CN | disclosed |