Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22552016 | 1.00 | ADORA2A (0.57) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL30880775 | 0.89 | ADORA2A (0.48) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL22551908 | 0.89 | ADORA2A (0.48) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL22551946 | 0.86 | ADORA2A (0.62) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL29906690 | 0.86 | ADORA2A (0.62) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL22551795 | 0.86 | ADORA2A (0.59) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21722486 | 0.83 | ADORA2A (0.81) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL29907652 | 0.76 | ADORA2A (0.66) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22551964 | 0.76 | ADORA2A (0.66) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21722379 | 0.76 | ADORA2A (0.66) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-115181092-A | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-112279837-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-08-09 | — | — | CN | disclosed |