Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.64 |
| ▸ | CNR2 | P34972 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541651 | 1.00 | PTGER4 (0.64) | PTGER4CNR2CYP2D6PIM1PIM3 | |
| SCHEMBL11829790 | 0.87 | PTGER4 (0.72) | PTGER4CNR2KDM4EPOLBPKM | |
| SCHEMBL5119647 | 0.86 | PTGER4 (0.70) | PTGER4CNR2KDM4EPOLBPKM | |
| SCHEMBL5660529 | 0.86 | PTGER4 (0.70) | PTGER4CNR2KDM4EPOLBPKM | |
| SCHEMBL9019646 | 0.85 | PTGER4 (0.69) | PTGER4CNR2KDM4EPOLBPKM | |
| SCHEMBL31201905 | 0.85 | PTGER4 (0.69) | PTGER4CNR2KDM4EPOLBPKM | |
| SCHEMBL600436 | 0.84 | PTGER4 (0.67) | PTGER4CNR2 | |
| SCHEMBL16099314 | 0.83 | PTGER4 (0.67) | PTGER4CNR2KDM4EPOLBPKM | |
| SCHEMBL541688 | 0.83 | CYP2D6 (0.74) | CNR2CYP2D6PIM1PIM3DRD3 | |
| SCHEMBL29907915 | 0.83 | CYP2D6 (0.74) | CNR2CYP2D6PIM1PIM3DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989161-B | c-MYC transcription inhibitor, preparation method and application thereof | 中山大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-114989161-A | C-MYC transcription inhibitor and preparation method and application thereof | 中山大学 | 2022-09-02 | — | — | CN | disclosed |