SCHEMBL29908133

SCHEMBL29908133

O=C(N[C@@H](Cc1ccc(F)c(F)c1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 5/20 0.54
MDM4 O15151 3/20 0.54
TP53 P04637 3/20 0.54
PTPN1 P18031 3/20 0.49
CASP3 P42574 2/20 0.47
SLC17A5 Q9NRA2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29400931 1.00 MDM2 (0.54) MDM2MDM4TP53PTPN1CASP3
SCHEMBL3728822 1.00 MDM2 (0.54) MDM2MDM4TP53PTPN1CASP3
SCHEMBL120627 1.00 MDM2 (0.54) MDM2MDM4TP53PTPN1CASP3
SCHEMBL29445603 1.00 MDM2 (0.54) MDM2MDM4TP53PTPN1CASP3
SCHEMBL119539 1.00 MDM2 (0.54) MDM2MDM4TP53PTPN1CASP3
SCHEMBL25360926 0.92 MDM2 (0.56) MDM2MDM4TP53PTPN1CASP3
SCHEMBL15083325 0.92 MDM2 (0.52) MDM2MDM4TP53PTPN1CASP3
SCHEMBL30898982 0.92 MDM2 (0.52) MDM2MDM4TP53PTPN1CASP3
SCHEMBL25360931 0.92 MDM2 (0.56) MDM2MDM4TP53PTPN1CASP3
SCHEMBL16287905 0.92 MDM2 (0.52) MDM2MDM4TP53PTPN1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115053184-B Composition for forming EUV resist underlayer film 日产化学株式会社 2024-12-06 CN disclosed
CN-115053184-A Composition for forming EUV resist underlayer film 日产化学株式会社 2022-09-13 CN disclosed