Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.72 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.50 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 6/20 | 0.42 |
| ▸ | ITK | Q08881 | 6/20 | 0.42 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18987081 | 0.84 | USP30 (1.00) | USP30OTUD7BPCSK9 | |
| SCHEMBL29908149 | 0.81 | USP30 (0.74) | USP30OTUD7BPCSK9LCKITK | |
| SCHEMBL19017747 | 0.79 | USP30 (0.77) | USP30OTUD7BPCSK9LCKITK | |
| SCHEMBL24977487 | 0.76 | USP30 (0.72) | USP30OTUD7BPCSK9LCKITK | |
| SCHEMBL18987364 | 0.75 | USP30 (0.65) | USP30OTUD7BPCSK9LCKITK | |
| SCHEMBL17631790 | 0.74 | USP30 (0.75) | USP30OTUD7BLCKITKMAP4K1 | |
| SCHEMBL17631787 | 0.74 | USP30 (0.75) | USP30OTUD7BLCKITKMAP4K1 | |
| SCHEMBL18987257 | 0.73 | USP30 (1.00) | USP30OTUD7BPCSK9LCKITK | |
| SCHEMBL18987182 | 0.72 | USP30 (0.65) | USP30OTUD7BPCSK9LCKITK | |
| SCHEMBL20051382 | 0.70 | USP30 (1.00) | USP30OTUD7BLCKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4122929-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2023-01-25 | — | — | EP | disclosed |
| EP-3390391-B1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2022-09-14 | — | — | EP | disclosed |