Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K2 | P36507 | 19/20 | 0.81 |
| ▸ | MAP2K1 | Q02750 | 19/20 | 0.81 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | BRAF | P15056 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | ACTR3 | P61158 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16579974 | 1.00 | MAP2K2 (0.81) | MAP2K2MAP2K1CHRM2CHRM1BRAF | |
| SCHEMBL16571607 | 0.90 | MAP2K1 (0.83) | MAP2K2MAP2K1CHRM2CHRM1BRAF | |
| SCHEMBL187560 | 0.90 | MAP2K1 (1.00) | MAP2K2MAP2K1CHRM2CHRM1BRAF | |
| SCHEMBL29413423 | 0.90 | MAP2K1 (1.00) | MAP2K2MAP2K1CHRM2CHRM1BRAF | |
| SCHEMBL17974842 | 0.89 | MAP2K1 (0.93) | MAP2K2MAP2K1CHRM2CHRM1BRAF | |
| SCHEMBL23398084 | 0.88 | MAP2K2 (0.62) | MAP2K2MAP2K1CHRM2CHRM1BRAF | |
| SCHEMBL16571767 | 0.87 | MAP2K1 (0.81) | MAP2K2MAP2K1CHRM2CHRM1BRAF | |
| SCHEMBL16579968 | 0.87 | MAP2K1 (0.81) | MAP2K2MAP2K1CHRM2CHRM1BRAF | |
| Hydrochloric Acid SCHEMBL16571619 | 0.86 | MAP2K1 (0.80) | MAP2K2MAP2K1CHRM2CHRM1BRAF | |
| Hydrochloric Acid SCHEMBL29908904 | 0.86 | MAP2K1 (0.80) | MAP2K2MAP2K1CHRM2CHRM1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230100458-A1 | NOVEL ANTHRANILIC AMIDES AND THE USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-03-30 | — | — | US | disclosed |
| US-11465978-B2 | Anthranilic amides and the use thereof | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2022-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230100458-A1 | NOVEL ANTHRANILIC AMIDES AND THE USE THEREOF | API5, MAPKAPK5, MAP3K5 | MAP2K2 144/4885MAP2K1 315/4885CHRM2 3742/4885 |
| US-11465978-B2 | Anthranilic amides and the use thereof | MAPKAPK5, MAP3K5, API5 | MAP2K2 149/4885MAP2K1 301/4885CHRM2 3680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.