SCHEMBL29909150

SCHEMBL29909150

NNc1nc(N(c2cccc(I)c2)C(F)(F)F)c2cc(F)c(Cl)cc2n1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23576868 1.00 GAA (0.30) GAAMAPT
SCHEMBL23576689 0.88 GAA (0.38) GAAMAPT
SCHEMBL29909530 0.88 GAA (0.38) GAAMAPT
SCHEMBL29909610 0.86
SCHEMBL23577541 0.86
SCHEMBL23601955 0.74 GAA (0.35) GAAMAPT
SCHEMBL29909124 0.72
SCHEMBL23576918 0.72
SCHEMBL23601913 0.70 EGFR (0.39) MAPT
SCHEMBL29909396 0.70 EGFR (0.39) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324767-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-07-12 CN disclosed
CN-115362003-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2022-11-18 CN disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed