SCHEMBL29909183

SCHEMBL29909183

C[C@@H](Oc1ccc(-c2cccc(N(C)c3nc4nncn4c4cc(Cl)ccc34)c2)cn1)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.34
FNTB P49356 1/20 0.34
PSD A5PKW4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23577297 1.00 FNTA (0.34) FNTAFNTBPSD
SCHEMBL23577294 1.00 FNTA (0.34) FNTAFNTBPSD
SCHEMBL23577736 0.88 SCN9A (0.35) FNTAFNTBPSD
SCHEMBL23601031 0.88 KDR (0.39) FNTAFNTBPSD
SCHEMBL31229686 0.88 KDR (0.39) FNTAFNTBPSD
SCHEMBL31169421 0.85 FNTA (0.36) FNTAFNTBPSD
SCHEMBL23601434 0.85 FNTA (0.36) FNTAFNTBPSD
SCHEMBL29909557 0.85 FNTA (0.37) FNTAFNTB
SCHEMBL23576895 0.85 FNTA (0.37) FNTAFNTB
SCHEMBL23601379 0.85 FNTA (0.36) FNTAFNTBPSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed