Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067850 | 0.73 | NPC1 (0.35) | HTR2CTDP1CYP2D6NPC1 | |
| SCHEMBL17763773 | 0.66 | — | — | |
| SCHEMBL31203 | 0.65 | TDP1 (0.55) | TDP1CYP2D6CA2 | |
| SCHEMBL22204319 | 0.63 | — | — | |
| SCHEMBL17525157 | 0.63 | — | — | |
| SCHEMBL31397625 | 0.62 | — | — | |
| SCHEMBL11661836 | 0.62 | TDP1 (0.33) | TDP1CA2 | |
| SCHEMBL15957607 | 0.61 | NPSR1 (0.52) | HTR2CTDP1CYP2D6CA2 | |
| SCHEMBL30938253 | 0.60 | — | — | |
| SCHEMBL11315591 | 0.59 | TDP1 (0.42) | HTR2CTDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184909-A1 | CROSSLINKABLE POLYMERS WITH HETEROAROMATIC GROUPS | HENKEL AG & CO. KGAA (DE) | 2010-07-22 | — | — | US | disclosed |
| EP-2195353-A1 | CROSSLINKABLE POLYMERS WITH HETEROAROMATIC GROUPS | Henkel AG & Co. KGaA (DE) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009043655-A1 | CROSSLINKABLE POLYMERS WITH HETEROAROMATIC GROUPS | HENKEL AG & CO. KGAA (DE) | 2009-04-09 | — | — | WO | disclosed |