Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 4/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979027 | 0.81 | PDE5A (0.41) | PDE5AEGFR | |
| SCHEMBL30979122 | 0.79 | PDE5A (0.43) | PDE5ACSNK2A2CSNK2BCSNK2A1EGFR | |
| SCHEMBL29213130 | 0.79 | PDE5A (0.43) | PDE5ACSNK2A2CSNK2BCSNK2A1EGFR | |
| SCHEMBL30978980 | 0.79 | PDE5A (0.43) | PDE5ACSNK2A2CSNK2BCSNK2A1EGFR | |
| SCHEMBL23577096 | 0.78 | PDE5A (0.40) | PDE5ACSNK2A2CSNK2BCSNK2A1EGFR | |
| SCHEMBL29909190 | 0.78 | PDE5A (0.40) | PDE5ACSNK2A2CSNK2BCSNK2A1EGFR | |
| SCHEMBL29909866 | 0.77 | PDE5A (0.37) | PDE5ACSNK2A2CSNK2BCSNK2A1EGFR | |
| SCHEMBL30979143 | 0.77 | PDE5A (0.41) | PDE5ACSNK2A2CSNK2BCSNK2A1EGFR | |
| SCHEMBL30979000 | 0.76 | PDE5A (0.39) | PDE5AEGFRPDGFRBKDR | |
| SCHEMBL29210703 | 0.76 | PDE5A (0.40) | PDE5ACSNK2A2CSNK2BCSNK2A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |