Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576972 | 1.00 | CSNK2A1 (0.37) | CSNK2A1CSNK2A2CSNK2BCYP2A6PDE5A | |
| SCHEMBL23577290 | 0.91 | CSNK2A1 (0.37) | CSNK2A1CSNK2A2CSNK2BPDE5ASMN1; SMN2 | |
| SCHEMBL29909900 | 0.91 | CSNK2A1 (0.37) | CSNK2A1CSNK2A2CSNK2BPDE5ASMN1; SMN2 | |
| SCHEMBL23576806 | 0.89 | MAPT (0.35) | CSNK2A1CSNK2A2CSNK2BPDE5ASMN1; SMN2 | |
| SCHEMBL30961002 | 0.89 | MAPT (0.35) | CSNK2A1CSNK2A2CSNK2BPDE5ASMN1; SMN2 | |
| SCHEMBL23577044 | 0.88 | ABCG2 (0.41) | CYP2A6MAPT | |
| SCHEMBL29909547 | 0.88 | ABCG2 (0.41) | CYP2A6MAPT | |
| SCHEMBL23601402 | 0.88 | PDE5A (0.34) | CSNK2A1CSNK2A2CSNK2BPDE5ASMN1; SMN2 | |
| SCHEMBL23577410 | 0.88 | PDE5A (0.34) | CSNK2A1CSNK2A2CSNK2BPDE5ASMN1; SMN2 | |
| SCHEMBL23577408 | 0.88 | PDE5A (0.34) | CSNK2A1CSNK2A2CSNK2BPDE5ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-B1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES INC (JP) | 2024-09-18 | — | — | EP | disclosed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |