⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577580 | 1.00 | — | — | |
| SCHEMBL23577819 | 0.92 | — | — | |
| SCHEMBL29909459 | 0.92 | — | — | |
| SCHEMBL23601699 | 0.90 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL23577095 | 0.90 | — | — | |
| SCHEMBL29909753 | 0.90 | — | — | |
| SCHEMBL23576731 | 0.90 | — | — | |
| SCHEMBL23601988 | 0.87 | — | — | |
| SCHEMBL24807465 | 0.87 | — | — | |
| SCHEMBL24721193 | 0.84 | TNIK (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12054490-B2 | Diacylglycerol kinase modulating compounds | GILEAD SCIENCES, INC. (US) | 2024-08-06 | — | — | US | disclosed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |