SCHEMBL29909751

SCHEMBL29909751

CN(c1cccc(F)c1)c1nc2nncn2c2cc(Br)c(F)cc12

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.42
HCRTR1 O43613 1/20 0.32
MAPT P10636 3/20 0.31
EGFR P00533 1/20 0.30
KDR P35968 1/20 0.30
PER2 O15055 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23576978 1.00 ABCG2 (0.42) ABCG2HCRTR1MAPTEGFRKDR
SCHEMBL23601280 0.91 ABCG2 (0.46) ABCG2HCRTR1MAPTPER2
SCHEMBL29909063 0.91 ABCG2 (0.46) ABCG2HCRTR1MAPTPER2
SCHEMBL23601252 0.90 ABCG2 (0.35) ABCG2MAPT
SCHEMBL29909434 0.87 ABCG2 (0.42) ABCG2HCRTR1MAPT
SCHEMBL29909219 0.87 ABCG2 (0.42) ABCG2HCRTR1MAPT
SCHEMBL23576699 0.87 ABCG2 (0.42) ABCG2HCRTR1MAPT
SCHEMBL23577999 0.87 ABCG2 (0.42) ABCG2HCRTR1MAPT
SCHEMBL23577019 0.86 ABCG2 (0.43) ABCG2HCRTR1MAPTEGFRKDR
SCHEMBL29909802 0.86 ABCG2 (0.43) ABCG2HCRTR1MAPTEGFRKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4445902-A2 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2024-10-16 EP disclosed
CN-118324767-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-07-12 CN disclosed
CN-115362003-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2022-11-18 CN disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed