⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576975 | 1.00 | — | — | |
| SCHEMBL23577331 | 0.92 | MAPT (0.30) | — | |
| SCHEMBL29909404 | 0.92 | MAPT (0.30) | — | |
| SCHEMBL29909350 | 0.89 | — | — | |
| SCHEMBL23576882 | 0.89 | — | — | |
| SCHEMBL23577192 | 0.88 | — | — | |
| SCHEMBL29909702 | 0.88 | — | — | |
| SCHEMBL23577182 | 0.86 | — | — | |
| SCHEMBL29909244 | 0.86 | — | — | |
| SCHEMBL23601717 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |