SCHEMBL29909867

SCHEMBL29909867

CC(C)c1nnc2nc(N(C)c3ccccc3)c3c(Br)c(F)ccc3n12

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29909048 0.86 MAPT (0.35) PIM1
SCHEMBL29909315 0.83 RXFP1 (0.32)
SCHEMBL29909481 0.81
SCHEMBL23578000 0.80 ABCG2 (0.33)
SCHEMBL30979143 0.77 PDE5A (0.41)
SCHEMBL30978989 0.67 ABCG2 (0.40)
SCHEMBL23601392 0.65 MAPT (0.37)
SCHEMBL30979122 0.65 PDE5A (0.43)
SCHEMBL30978980 0.65 PDE5A (0.43)
SCHEMBL29213130 0.65 PDE5A (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324767-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-07-12 CN disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed