Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | GIPR | P48546 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1334077 | 1.00 | MCHR1 (0.35) | MCHR1PLGPLAUPLATALK | |
| SCHEMBL2016514 | 1.00 | MCHR1 (0.35) | MCHR1PLGPLAUPLATALK | |
| SCHEMBL12573753 | 1.00 | MCHR1 (0.35) | MCHR1PLGPLAUPLATALK | |
| SCHEMBL1334027 | 0.98 | PLG (0.36) | MCHR1PLGPLAUPLATMGAT2 | |
| SCHEMBL29910266 | 0.98 | PLG (0.36) | MCHR1PLGPLAUPLATMGAT2 | |
| SCHEMBL12573736 | 0.96 | ALK (0.33) | MCHR1PLGPLAUPLATALK | |
| SCHEMBL17059995 | 0.96 | MGAT2 (0.34) | MCHR1PLGPLAUPLATALK | |
| SCHEMBL1332874 | 0.96 | PLG (0.36) | MCHR1PLGPLAUPLATMGAT2 | |
| SCHEMBL30914182 | 0.96 | PLG (0.36) | MCHR1PLGPLAUPLATMGAT2 | |
| SCHEMBL1333834 | 0.96 | ALK (0.33) | MCHR1PLGPLAUPLATALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895896-B1 | A PHOTOCHROMIC ARTICLE HAVING AT LEAST PARTIALLY CROSSED POLARIZED PHOTOCHROMIC-DICHROIC AND FIXED-POLARIZED LAYERS | TRANSITIONS OPTICAL INC (US) | 2022-11-02 | — | — | EP | disclosed |