Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 19/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20085961 | 1.00 | IRAK4 (0.53) | IRAK4KCNH2SCN9A | |
| SCHEMBL20085966 | 0.95 | IRAK4 (0.53) | IRAK4KCNH2 | |
| SCHEMBL29911962 | 0.95 | IRAK4 (0.53) | IRAK4KCNH2 | |
| SCHEMBL20085968 | 0.93 | IRAK4 (0.56) | IRAK4KCNH2SCN9A | |
| SCHEMBL29912108 | 0.93 | IRAK4 (0.56) | IRAK4KCNH2SCN9A | |
| SCHEMBL30261571 | 0.86 | IRAK4 (0.58) | IRAK4KCNH2 | |
| SCHEMBL20085939 | 0.86 | IRAK4 (0.58) | IRAK4KCNH2 | |
| SCHEMBL20085934 | 0.85 | IRAK4 (0.57) | IRAK4KCNH2 | |
| SCHEMBL20085954 | 0.85 | IRAK4 (0.59) | IRAK4KCNH2 | |
| SCHEMBL20086084 | 0.85 | IRAK4 (0.54) | IRAK4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115531387-A | Pyrazole amide compounds useful as IRAK inhibitors | 里格尔药品股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-110234637-B | Pyrazole amide compounds useful as IRAK inhibitors | 里格尔药品股份有限公司 | 2022-11-01 | — | — | CN | disclosed |