SCHEMBL29913451

SCHEMBL29913451

Nc1nccn2c([C@H]3CC[C@@H](CO)OC3)nc(-c3ccc(Oc4ccccc4)cc3F)c12

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TNK2 Q07912 20/20 0.72
CYP2C19 P33261 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23625327 1.00 TNK2 (0.72) TNK2CYP2C19
SCHEMBL29913383 1.00 TNK2 (0.72) TNK2CYP2C19
SCHEMBL29913460 1.00 TNK2 (0.72) TNK2CYP2C19
SCHEMBL29913310 1.00 TNK2 (0.72) TNK2CYP2C19
SCHEMBL25981058 0.91 TNK2 (0.72) TNK2CYP2C19
SCHEMBL30065194 0.90 TNK2 (0.69) TNK2
SCHEMBL30065113 0.90 TNK2 (0.69) TNK2
SCHEMBL30065131 0.90 TNK2 (0.69) TNK2
SCHEMBL30065114 0.90 TNK2 (0.69) TNK2
SCHEMBL25981040 0.90 TNK2 (0.57) TNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120118089-A BTK inhibitors 迪哲(江苏)医药股份有限公司 2025-06-10 CN claimed
CN-114945574-B BTK inhibitors 迪哲(江苏)医药股份有限公司 2025-02-07 CN claimed
CN-120118089-A BTK inhibitors 迪哲(江苏)医药股份有限公司 2025-06-10 CN disclosed
CN-114945574-B BTK inhibitors 迪哲(江苏)医药股份有限公司 2025-02-07 CN disclosed
CN-114945574-A BTK inhibitors 迪哲(江苏)医药股份有限公司 2022-08-26 CN disclosed