Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31016704 | 1.00 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3GRIN2BSLC18A3 | |
| SCHEMBL21625220 | 0.91 | SLC18A3 (0.50) | SLC6A4SLC6A2SLC6A3GRIN2BSLC18A3 | |
| SCHEMBL31016686 | 0.91 | SLC18A3 (0.50) | SLC6A4SLC6A2SLC6A3GRIN2BSLC18A3 | |
| SCHEMBL3581153 | 0.90 | GRIN2B (0.56) | SLC6A4SLC6A2SLC6A3GRIN2BSLC18A3 | |
| Hydrochloric Acid SCHEMBL29057102 | 0.90 | SLC18A3 (0.49) | SLC6A4SLC6A2SLC6A3GRIN2BSLC18A3 | |
| SCHEMBL10574037 | 0.84 | SLC6A2 (0.69) | SLC6A4SLC6A2SLC6A3GRIN2BSLC18A3 | |
| SCHEMBL1967143 | 0.81 | GRIN2B (0.63) | GRIN2BSLC18A3CHIATAAR1SIGMAR1 | |
| SCHEMBL27544721 | 0.81 | GRIN2B (0.58) | SLC6A4SLC6A2SLC6A3GRIN2BSLC18A3 | |
| SCHEMBL3041474 | 0.79 | GRIN2B (0.45) | SLC6A4SLC6A2SLC6A3GRIN2BSLC18A3 | |
| SCHEMBL27820511 | 0.78 | SLC18A3 (0.64) | GRIN2BSLC18A3CHIATAAR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4305029-A1 | NEW 2,3-DIHYDRO-1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVES AS SIGMA LIGANDS | Acondicionamiento Tarrasense (ES) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022189392-A1 | NEW 2,3-DIHYDRO-1H-PYRROLO[3,2-b]PYRIDINE DERIVATIVES AS SIGMA LIGANDS | ACONDICIONAMIENTO TARRASENSE (ES) | 2022-09-15 | — | — | WO | disclosed |