Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.71 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.63 |
| ▸ | BRD4 | O60885 | 2/20 | 0.59 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20128669 | 1.00 | CRBN (0.71) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL30918268 | 1.00 | CRBN (0.71) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL30066328 | 0.83 | CRBN (1.00) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL20128668 | 0.83 | CRBN (1.00) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL30760758 | 0.83 | CRBN (1.00) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL29568563 | 0.83 | CRBN (1.00) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL20812427 | 0.81 | CRBN (0.66) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL25626935 | 0.81 | CRBN (0.53) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL25627049 | 0.81 | CRBN (0.53) | CRBNDDB1BRD4IKZF3 | |
| SCHEMBL23874568 | 0.80 | CRBN (0.65) | CRBNDDB1BRD4IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118638043-A | Compounds and methods for targeted degradation of androgen receptor | 阿尔维纳斯运营股份有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-118059104-A | Compounds and methods for targeted degradation of androgen receptor | 阿尔维纳斯运营股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-115175901-B | Compounds and methods for targeted degradation of androgen receptor | 阿尔维纳斯运营股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-4077309-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas Operations, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| CN-115175901-A | Compounds and methods for targeted degradation of androgen receptor | 阿尔维纳斯运营股份有限公司 | 2022-10-11 | — | — | CN | disclosed |