Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | RAMP3 | O60896 | 8/20 | 0.49 |
| ▸ | CALCR | P30988 | 8/20 | 0.49 |
| ▸ | NPY2R | P49146 | 7/20 | 0.47 |
| ▸ | NPY4R | P50391 | 7/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.47 |
| ▸ | NPY1R | P25929 | 5/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29914214 | 0.98 | MAPK8 (0.52) | MAPK8MAPK9MAPK10RAMP3CALCR | |
| SCHEMBL29569390 | 0.91 | MAPK8 (0.48) | MAPK8MAPK9MAPK10RAMP3CALCR | |
| SCHEMBL29569097 | 0.89 | MAPK8 (0.47) | MAPK8MAPK9MAPK10RAMP3CALCR | |
| SCHEMBL29569702 | 0.88 | MAPK8 (0.47) | MAPK8MAPK9MAPK10RAMP3CALCR | |
| SCHEMBL29914211 | 0.87 | PTPN1 (0.48) | MAPK8MAPK9MAPK10RAMP3CALCR | |
| SCHEMBL29776766 | 0.87 | MAPK8 (0.58) | MAPK8MAPK9MAPK10RAMP3CALCR | |
| SCHEMBL29914213 | 0.86 | BACE1 (0.50) | — | |
| SCHEMBL29568390 | 0.86 | NPY2R (0.47) | MAPK8MAPK9MAPK10RAMP3CALCR | |
| SCHEMBL30844275 | 0.86 | NPY2R (0.52) | MAPK8MAPK9MAPK10NPY2RNPY4R | |
| SCHEMBL30075807 | 0.85 | PTPN1 (0.47) | MAPK8MAPK9MAPK10RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11426441-B2 | Composition comprising protein phosphatase 1 inhibitory peptide for treating vascular diseases | BETHPHAGEN INC. (KR) | 2022-08-30 | — | — | US | disclosed |