SCHEMBL29914258

SCHEMBL29914258

CC(=O)Nc1ncc(CN2C[C@@]3(Cc4cc(C(F)(F)F)ncc4O3)C[C@@H]2C)s1

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 20/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23304867 1.00 OGA (0.46) OGA
SCHEMBL23304925 0.87 OGA (0.46) OGA
SCHEMBL29914289 0.87 OGA (0.46) OGA
SCHEMBL29914287 0.87 OGA (0.39) OGA
SCHEMBL23304794 0.87 OGA (0.39) OGA
SCHEMBL23304743 0.87 OGA (0.43) OGA
SCHEMBL29914331 0.87 OGA (0.43) OGA
SCHEMBL29914329 0.87 OGA (0.43) OGA
SCHEMBL23305242 0.86 OGA (0.46) OGA
SCHEMBL23305518 0.86 OGA (0.45) OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929709-B Spirocyclic O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranoside inhibitors 比奥根MA公司 2024-08-30 — — CN claimed
CN-114929709-B Spirocyclic O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranoside inhibitors 比奥根MA公司 2024-08-30 — — CN disclosed
EP-4051682-A1 SPIROCYCLIC O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS Biogen MA Inc. (US) 2022-09-07 — — EP disclosed
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