SCHEMBL29914299

SCHEMBL29914299

CC(=O)Nc1nc(F)c(CN2CCCC3(C2)OCc2cncnc23)s1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 20/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23305313 1.00 OGA (0.39) OGA
SCHEMBL23305003 0.87 OGA (0.37) OGA
SCHEMBL23305423 0.85 OGA (0.50) OGA
SCHEMBL29914301 0.85 OGA (0.50) OGA
SCHEMBL23304714 0.85 OGA (0.36) OGA
SCHEMBL23305009 0.85 OGA (0.36) OGA
SCHEMBL23305000 0.85 OGA (0.36) OGA
SCHEMBL23306083 0.83 OGA (0.36) OGA
SCHEMBL29914317 0.83 OGA (0.36) OGA
SCHEMBL23304903 0.82 HRH3 (0.40) OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929709-B Spirocyclic O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranoside inhibitors 比奥根MA公司 2024-08-30 — — CN claimed
CN-114929709-B Spirocyclic O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranoside inhibitors 比奥根MA公司 2024-08-30 — — CN disclosed
EP-4051682-A1 SPIROCYCLIC O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS Biogen MA Inc. (US) 2022-09-07 — — EP disclosed
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