Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 18/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23317516 | 1.00 | OGA (0.41) | OGAPIK3CGSIRT1SIRT3 | |
| SCHEMBL23304953 | 1.00 | OGA (0.41) | OGAPIK3CGSIRT1SIRT3 | |
| SCHEMBL23304882 | 0.87 | OGA (0.43) | OGASIRT1SIRT3 | |
| SCHEMBL23304797 | 0.85 | OGA (0.42) | OGAPIK3CG | |
| SCHEMBL29914291 | 0.85 | OGA (0.42) | OGAPIK3CG | |
| SCHEMBL29914288 | 0.84 | OGA (0.41) | OGA | |
| SCHEMBL23305221 | 0.84 | OGA (0.41) | OGA | |
| SCHEMBL23317323 | 0.83 | OGA (0.40) | OGA | |
| SCHEMBL23305420 | 0.83 | OGA (0.42) | OGA | |
| SCHEMBL29914335 | 0.83 | OGA (0.42) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051682-A1 | SPIROCYCLIC O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | Biogen MA Inc. (US) | 2022-09-07 | — | — | EP | disclosed |