Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK4 | Q16654 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 10/20 | 0.52 |
| ▸ | GRM1 | Q13255 | 10/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | QDPR | P09417 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1364792 | 1.00 | PDK4 (0.57) | PDK4NAMPTGRM5GRM1ESR2 | |
| SCHEMBL7831576 | 0.89 | PDK4 (0.58) | PDK4NAMPTGRM5GRM1HTR6 | |
| SCHEMBL2811392 | 0.88 | PDK4 (0.60) | PDK4NAMPTGRM5GRM1HTR6 | |
| SCHEMBL22619074 | 0.88 | PDK4 (0.48) | PDK4NAMPTGRM5GRM1ESR2 | |
| SCHEMBL2239831 | 0.87 | NAMPT (0.66) | PDK4NAMPTGRM5GRM1HTR6 | |
| SCHEMBL30014227 | 0.87 | PDK4 (0.56) | PDK4NAMPTGRM5GRM1HTR6 | |
| SCHEMBL13261659 | 0.87 | PDK4 (0.56) | PDK4NAMPTGRM5GRM1HTR6 | |
| SCHEMBL902871 | 0.87 | PDK4 (0.56) | PDK4NAMPTGRM5GRM1HTR6 | |
| SCHEMBL3988457 | 0.87 | PDK4 (0.56) | PDK4NAMPTGRM5GRM1HTR6 | |
| SCHEMBL904049 | 0.86 | NAMPT (0.61) | PDK4NAMPTGRM5GRM1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119421709-A | Indazole-containing macrocyclic compounds and uses thereof | 荣山医药股份有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-115867546-B | Salt and crystalline forms of GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-110612294-B | Human cerebulin ligands and bifunctional compounds comprising same | 阿尔维纳斯运营股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-115974840-A | Human cereblon ligand and bifunctional compound comprising same | 阿尔维纳斯运营股份有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-115867546-A | Salts and crystalline forms of GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113831337-B | GLP-1 receptor agonist, and pharmaceutical composition and use thereof | 广州市恒诺康医药科技有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-111094300-B | Benzo-heteroaryl derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-09-16 | — | — | CN | disclosed |