SCHEMBL2991635

SCHEMBL2991635

CCc1c(Cc2ccccc2)cccc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 2/20 0.48
PDCD1 Q15116 1/20 0.44
CD274 Q9NZQ7 1/20 0.44
FOLH1 Q04609 1/20 0.41
DPP4 P27487 1/20 0.41
TP53 P04637 1/20 0.40
HTR7 P34969 2/20 0.39
HTR2A P28223 1/20 0.39
CALM1 P0DP23 1/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
BCL2 P10415 1/20 0.37
BCL2L1 Q07817 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
DRD2 P14416 1/20 0.36
DRD1 P21728 1/20 0.36
DRD3 P35462 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5562618 0.87 SLC5A2 (0.47) SLC5A2PDCD1CD274FOLH1DPP4
SCHEMBL9185899 0.86 TP53 (0.40) SLC5A2TP53HTR2ACALM1BCL2
SCHEMBL473270 0.85 PDCD1 (0.50) SLC5A2PDCD1CD274FOLH1DPP4
SCHEMBL10599555 0.85 TP53 (0.50) TP53HTR2ACALM1BCL2BCL2L1
SCHEMBL11207700 0.84 HTT (0.43) SLC5A2PDCD1CD274FOLH1DPP4
SCHEMBL11382363 0.83 PDCD1 (0.48) SLC5A2PDCD1CD274FOLH1DPP4
SCHEMBL27618792 0.83 PDCD1 (0.48) SLC5A2PDCD1CD274FOLH1DPP4
Water SCHEMBL27696696 0.83 PDCD1 (0.48) SLC5A2PDCD1CD274FOLH1DPP4
Ammonia Solution, Strong SCHEMBL27966639 0.83 PDCD1 (0.48) SLC5A2PDCD1CD274FOLH1DPP4
Ethane SCHEMBL3687852 0.83 PDCD1 (0.48) SLC5A2PDCD1CD274FOLH1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
EP-0558816-B1 Process for the preparation of monobenzylated alkylbiphenyls and their use HUELS CHEMISCHE WERKE AG (DE) 1995-10-11 EP disclosed
EP-0526705-B1 Use of substituted biphenyls as heat transfer liquids HUELS CHEMISCHE WERKE AG (DE) 1995-06-28 EP disclosed
EP-0558816-A1 Process for the preparation of monobenzylated alkylbiphenyls and their use HÜLS AKTIENGESELLSCHAFT (DE) 1993-09-08 EP disclosed
US-4371726-A Composition suitable for mechanical power transmission and process for operating traction drives NIPPON STEEL CHEMICAL CO., LTD. (JP) 1983-02-01 US disclosed