Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21598025 | 0.90 | HTT (0.48) | LPAR1HTTMAPTALDH1A1KMT2A | |
| SCHEMBL21598071 | 0.79 | IDH1 (0.42) | LPAR1MAPTPOLB | |
| SCHEMBL21598041 | 0.79 | SMN1; SMN2 (0.38) | LPAR1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL21598006 | 0.74 | MAPT (0.53) | HTTMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL21217705 | 0.72 | HTT (0.72) | LPAR1HTTMAPTALDH1A1KMT2A | |
| SCHEMBL526203 | 0.71 | LPAR1 (0.49) | LPAR1HTTMAPTALDH1A1KMT2A | |
| SCHEMBL21598020 | 0.69 | LPAR1 (0.47) | LPAR1HTTMAPTALDH1A1KMT2A | |
| SCHEMBL2076016 | 0.66 | LPAR1 (0.57) | LPAR1HTTMAPTALDH1A1KMT2A | |
| SCHEMBL31079121 | 0.66 | LPAR1 (0.57) | LPAR1HTTMAPTALDH1A1KMT2A | |
| SCHEMBL3504431 | 0.66 | LPAR1 (0.57) | LPAR1HTTMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807251-B1 | PHENYL AND PYRIDINYL SUBSTITUTED IMIDAZOLES AS MODULATORS OF RORYT | JANSSEN PHARMACEUTICA NV (BE) | 2022-09-07 | — | — | EP | disclosed |