Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 12/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.58 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23306557 | 0.94 | S1PR5 (0.64) | S1PR5S1PR1S1PR3HSD17B10HPGD | |
| SCHEMBL15166548 | 0.85 | S1PR5 (0.64) | S1PR5S1PR1S1PR3PRMT5GRM5 | |
| SCHEMBL23306543 | 0.82 | S1PR5 (0.55) | S1PR5S1PR1S1PR3HSD17B10HPGD | |
| SCHEMBL23348429 | 0.81 | S1PR5 (0.67) | S1PR5S1PR1S1PR3HSD17B10HPGD | |
| SCHEMBL321185 | 0.78 | S1PR1 (0.64) | S1PR5S1PR1S1PR3ALDH1A1MAPT | |
| SCHEMBL15164308 | 0.78 | ESR2 (0.50) | S1PR5S1PR1S1PR3GRM5MAPT | |
| SCHEMBL23306662 | 0.76 | S1PR5 (0.42) | S1PR5S1PR1S1PR3GRM5KDM4E | |
| SCHEMBL30785585 | 0.76 | MEN1 (0.44) | S1PR5S1PR1S1PR3HSD17B10HPGD | |
| SCHEMBL18549983 | 0.76 | MAPT (0.52) | S1PR5S1PR1S1PR3PRMT5ALDH1A1 | |
| SCHEMBL15164311 | 0.75 | GRM5 (0.47) | S1PR5S1PR1S1PR3GRM5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051683-A1 | SOLID FORMS OF AN S1P-RECEPTOR MODULATOR | Escape Bio, Inc. (US) | 2022-09-07 | — | — | EP | disclosed |