Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 19/20 | 0.55 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27085898 | 1.00 | CBLB (0.55) | CBLBMAP4K1 | |
| SCHEMBL29920413 | 0.92 | CBLB (0.56) | CBLBMAP4K1 | |
| SCHEMBL27086294 | 0.92 | CBLB (0.56) | CBLBMAP4K1 | |
| SCHEMBL29920298 | 0.91 | CBLB (0.56) | CBLBMAP4K1 | |
| SCHEMBL27086345 | 0.91 | CBLB (0.56) | CBLBMAP4K1 | |
| SCHEMBL27312275 | 0.90 | CBLB (0.60) | CBLB | |
| SCHEMBL27086004 | 0.89 | CBLB (0.49) | CBLB | |
| SCHEMBL27086169 | 0.88 | CBLB (0.68) | CBLB | |
| SCHEMBL29920155 | 0.88 | CBLB (0.68) | CBLB | |
| SCHEMBL29920611 | 0.88 | CBLB (0.55) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858707-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| EP-4319756-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022217276-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-10-13 | — | — | WO | disclosed |