SCHEMBL29920182

SCHEMBL29920182

C#CCOc1ccc(-c2cc(NCC)nc(N3Cc4c(cccc4C(F)(F)F)C3=O)c2)c(-c2nncn2C)c1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27085961 1.00 CBLB (0.59) CBLB
SCHEMBL27086127 0.91 CBLB (0.63) CBLB
SCHEMBL29920204 0.91 CBLB (0.63) CBLB
SCHEMBL29920433 0.89 CBLB (0.57) CBLB
SCHEMBL27085938 0.89 CBLB (0.57) CBLB
SCHEMBL29920155 0.89 CBLB (0.68) CBLB
SCHEMBL27086169 0.89 CBLB (0.68) CBLB
SCHEMBL29920123 0.88 CBLB (0.64) CBLB
SCHEMBL27085881 0.88 CBLB (0.64) CBLB
SCHEMBL30825424 0.87 CBLB (0.63) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117858707-A CBL-B modulators and uses thereof 林伯士克莱奥公司 2024-04-09 — — CN disclosed
EP-4319756-A1 CBL-B MODULATORS AND USES THEREOF Nimbus Clio, Inc. (US) 2024-02-14 — — EP disclosed
WO-2022217276-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-10-13 — — WO disclosed
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