Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920625 | 0.89 | MAP3K14 (0.54) | MAP3K14CA12CA1CA7CA14 | |
| SCHEMBL29920603 | 0.89 | MAP3K14 (0.38) | MAP3K14CA12CA1CA7CA14 | |
| SCHEMBL29920520 | 0.87 | IDO1 (0.39) | MAP3K14RORC | |
| SCHEMBL29920739 | 0.84 | AKR1B1 (0.40) | MAP3K14CA12CA1CA7CA14 | |
| SCHEMBL29920606 | 0.84 | AKR1B1 (0.40) | MAP3K14CA12CA1CA7CA14 | |
| SCHEMBL29920670 | 0.79 | CA12 (0.35) | CA12CA1CA7CA14RORC | |
| SCHEMBL29920736 | 0.77 | AKR1B1 (0.34) | CA12CA1CA7CA14RORC | |
| SCHEMBL29920997 | 0.73 | CA12 (0.36) | CA12CA1CA7CA14RORC | |
| SCHEMBL29920828 | 0.73 | CA12 (0.36) | CA12CA1CA7CA14RORC | |
| SCHEMBL29920356 | 0.72 | AKR1B1 (0.46) | CA12CA1CA7CA14RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217248-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |