SCHEMBL29920742

SCHEMBL29920742

CCNc1cc(-c2ccccc2-c2nncn2C)cc(N2Cc3c(cc(CN4CCC[C@H](C)C4)cc3C(F)(F)F)C2=O)n1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27086104 1.00 CBLB (0.56) CBLB
SCHEMBL29920531 1.00 CBLB (0.56) CBLB
SCHEMBL27086098 1.00 CBLB (0.56) CBLB
SCHEMBL27086570 1.00 CBLB (0.56) CBLB
SCHEMBL27324997 0.93 CBLB (0.53) CBLB
SCHEMBL27086208 0.92 CBLB (0.56) CBLB
SCHEMBL29920906 0.92 CBLB (0.56) CBLB
SCHEMBL27086214 0.92 CBLB (0.56) CBLB
SCHEMBL29920241 0.91 CBLB (0.60) CBLB
SCHEMBL29920153 0.91 CBLB (0.60) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4319756-A1 CBL-B MODULATORS AND USES THEREOF Nimbus Clio, Inc. (US) 2024-02-14 — — EP disclosed
WO-2022217276-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-10-13 — — WO disclosed
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