Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rimtuzalcap SCHEMBL19686931 | 1.00 | IDH1 (0.43) | IDH1ADORA2AADORA1KMT2AKDM4E | |
| SCHEMBL19686421 | 0.96 | IDH1 (0.41) | IDH1ADORA2AADORA1KMT2AKDM4E | |
| SCHEMBL21165843 | 0.94 | IDH1 (0.42) | IDH1ADORA2AADORA1KMT2AKDM4E | |
| SCHEMBL19686443 | 0.90 | ADORA2A (0.42) | IDH1ADORA2AADORA1KMT2AKDM4E | |
| SCHEMBL24061661 | 0.90 | CHRM3 (0.46) | IDH1ADORA2AADORA1MAPTLMNA | |
| SCHEMBL19687055 | 0.89 | IDH1 (0.44) | IDH1ADORA2AADORA1KMT2AKDM4E | |
| SCHEMBL19686381 | 0.89 | ADORA2A (0.43) | ADORA2AADORA1KMT2AKDM4EMAPT | |
| SCHEMBL19687051 | 0.89 | IDH1 (0.43) | IDH1ADORA2AADORA1KMT2AKDM4E | |
| SCHEMBL19687044 | 0.89 | IDH1 (0.43) | IDH1ADORA2AADORA1KMT2AKDM4E | |
| SCHEMBL21578586 | 0.88 | HRH4 (0.44) | ADORA2AADORA1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118985622-A | Application of pyrazole compound in prevention and control of plant root knot nematode | 云南大学 | 2024-11-22 | — | — | CN | disclosed |
| CN-116178374-B | Small-conductance calcium-activated potassium ion channel agonist, synthesis and application thereof | 河北医科大学 | 2024-10-08 | — | — | CN | disclosed |
| US-20240182436-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUMITOMO PHARMA AMERICA, INC. (US) | 2024-06-06 | — | — | US | disclosed |
| CN-116178374-A | Small-conductance calcium-activated potassium ion channel agonist, synthesis and application thereof | 河北医科大学 | 2023-05-30 | — | — | CN | disclosed |
| WO-2022217248-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182436-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | ARSA, SNCA, F12 | IDH1 1643/4885ADORA2A 947/4885ADORA1 592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.