Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.64 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.64 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL17839978 | 1.00 | CRBN (0.64) | CRBNDDB1BRD4CA2HDAC8 | |
| SCHEMBL17839882 | 0.94 | CRBN (0.68) | CRBNDDB1BRD4CA2HDAC8 | |
| SCHEMBL29922205 | 0.94 | CRBN (0.68) | CRBNDDB1BRD4CA2HDAC8 | |
| SCHEMBL17854847 | 0.88 | CRBN (0.65) | CRBNDDB1BRD4CA2HDAC8 | |
| SCHEMBL20188342 | 0.88 | CRBN (0.72) | CRBNDDB1BRD4HDAC8STAT3 | |
| SCHEMBL17839575 | 0.88 | CRBN (0.72) | CRBNDDB1BRD4HDAC8STAT3 | |
| Trifluoroacetic Acid SCHEMBL19747583 | 0.87 | CRBN (0.63) | CRBNDDB1STAT3 | |
| Trifluoroacetic Acid SCHEMBL19747894 | 0.87 | CRBN (0.63) | CRBNDDB1STAT3 | |
| Trifluoroacetic Acid SCHEMBL29493530 | 0.87 | CRBN (0.63) | CRBNDDB1STAT3 | |
| Trifluoroacetic Acid SCHEMBL29493526 | 0.87 | CRBN (0.63) | CRBNDDB1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108350062-B | Targeted protein degradation to attenuate adverse inflammatory responses associated with adoptive T cell therapy | 达纳-法伯癌症研究所股份有限公司 | 2022-10-14 | — | — | CN | disclosed |