Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 11/20 | 0.66 |
| ▸ | JAK2 | O60674 | 10/20 | 0.66 |
| ▸ | JAK1 | P23458 | 4/20 | 0.66 |
| ▸ | JAK3 | P52333 | 3/20 | 0.66 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28359034 | 1.00 | TYK2 (0.66) | TYK2JAK2JAK1JAK3WNT3A | |
| SCHEMBL29552246 | 1.00 | TYK2 (0.66) | TYK2JAK2JAK1JAK3WNT3A | |
| SCHEMBL29551980 | 0.93 | TYK2 (0.57) | TYK2JAK2JAK1JAK3WNT3A | |
| SCHEMBL28362685 | 0.93 | TYK2 (0.57) | TYK2JAK2JAK1JAK3WNT3A | |
| SCHEMBL28359094 | 0.86 | TYK2 (0.74) | TYK2JAK2JAK1JAK3 | |
| SCHEMBL28884122 | 0.80 | TYK2 (1.00) | TYK2JAK2JAK1JAK3 | |
| SCHEMBL29552327 | 0.80 | TYK2 (0.74) | TYK2JAK2JAK1JAK3 | |
| SCHEMBL28884123 | 0.80 | TYK2 (0.74) | TYK2JAK2JAK1JAK3 | |
| SCHEMBL29552312 | 0.78 | TYK2 (0.58) | TYK2JAK2JAK1JAK3 | |
| SCHEMBL29552169 | 0.78 | TYK2 (0.58) | TYK2JAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818641-B | Pyridazine-3-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-10-14 | — | — | CN | disclosed |