Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548026 | 0.79 | SIRT2 (0.33) | — | |
| SCHEMBL24269769 | 0.79 | SIRT2 (0.33) | — | |
| SCHEMBL23802683 | 0.78 | MEN1 (0.30) | — | |
| SCHEMBL10561767 | 0.74 | HPGD (0.33) | — | |
| SCHEMBL30034644 | 0.74 | KDM1A (0.30) | — | |
| SCHEMBL23802694 | 0.74 | KDM1A (0.30) | — | |
| SCHEMBL27172718 | 0.73 | ESR1 (0.33) | — | |
| SCHEMBL26982160 | 0.73 | AHR (0.31) | HTR2CHTR2B | |
| SCHEMBL20441298 | 0.71 | — | — | |
| SCHEMBL29875091 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |